Advanced Daily Probiotic Supplement for Immune System Health
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Advanced Daily Probiotic Supplement
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Advanced Daily Probiotic supplement contains a proprietary blend of 4 strains and 35 billion CFU probiotics to support gut microflora and immune health.†

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$45.57

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46.98

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Gluten-Free

 

Advanced Daily Probiotic
Supplement Facts

Serving Size: 1 capsule
Servings Per Container: 30
Ingredients Amount Per
Serving
% Daily
Value
 Saccharomyces boulardii 250 mg(5 Billion CFU†) *
Total Propriety Blend 174 mg(15 Billion CFU†) *
    Lactobacillus acidophilus La-14**
    Bifidobacterium longum Bl-05**
    Lactiplantibacillus plantarum Lp-115**
Bifidobacterium lactis HN019S2 Lp-115‡ 50 mg(15 Billion CFU†) *

*Daily Value not established.
Other Ingredients: Capsule (hypromellose, gellan gum, and water), hydroxypropyl cellulose, ascorbyl palmitate, and silica.

**HOWARU® is the registered trademark of IFF or its affiliates.
‡HN019™ is a trademark of the Fonterra Group of companies and used under license.

Cooper Complete Gluten Free iconCooper Complete Non GMO Icon

This dietary supplement is gluten-free and Non-GMO.

While we strive to ensure the label information on this site represents the label on the product available for purchase, products are updated from time to time. Please consult the label on the product you purchase for the most accurate ingredient and allergen information.

Item Number: 304
SKU: 816899005022
GTIN-12 (UPC-A): 202634-60-PL-84121312 V0522

What It Is

Probiotics are live, beneficial microorganisms that live in our gut. This daily probiotic supplement features four probiotic strains, including the extensively studied HN019 strain of Bifidobacterium lactis, plus Saccharomyces boulardii (Sb), a non-pathogenic probiotic yeast, to complement a healthy gastrointestinal environment further. (Saccharomyces boulardii supports a healthy balance of gut microbiota.†) Acid-resistant, vegetarian capsules target delivery to the small intestine, as they alleviate exposure to the low pH environment of the stomach. Each capsule is sealed in a nitrogen-purged blister pack to protect from heat, moisture, and oxygen, factors known to compromise probiotic stability.

How to Use:

As a dietary supplement, take one (1) vegetarian acid-resistant capsule daily or as directed by your health care professional. Each box contains 30 servings.

How It Helps

This everyday Advanced Daily Probiotic supplement provides four strains and 35 billion CFU probiotics to support gut microflora and immune function.†

Immune Health

A meta-analysis of 18 randomized clinical trials including 1,047 participants (with 514 in the probiotic group) on Lactobacillus plantarum and immune health suggests L. plantarum enhances immune response by modulating pro-inflammatory and anti-inflammatory cytokines.†

Blood Pressure Support

Maintaining healthy blood pressure levels is associated with overall cardiovascular health. A review of nine clinical trials, including 534 adults  (18 years and older), found a significant reduction in systolic (3.56 mmHg) and diastolic (2.38 mmHg) compared to the placebo. The Heart Outcomes Prevention Evaluation (HOPE Study) found that reducing systolic blood pressure by 3.3 mmHg and diastolic blood pressure by 1.4 mmHg was associated with a 22% reduction in stroke, heart attack, or cardiovascular event resulting in death.

Allergic Rhinitis Relief

A review of 23 studies found some evidence that lactobacillus probiotics may help support nasal comfort and a healthy immune response during seasonal changes.†

Cholesterol Management

A meta-analysis of 15 studies with 976 subjects found lactobacillus probiotics reduced total cholesterol by about 10 mg/dL and LDL by about 9 mg/dL in patients with or without hypercholesterolemia. However, Lactobacillus probiotics did not change HDL cholesterol.

Lung and Respiratory Tract Support

A 2015 review of 12 studies indicated people taking probiotics may have fewer and shorter upper respiratory infections. Lactobacillus seems to prevent respiratory tract infections in most adults, while bifidobacteria seems to prevent respiratory tract infections in otherwise healthy adults.†

Digestive Health Support

Advanced Daily Probiotic supplement is intentionally formulated to contribute to a healthy digestive tract and support optimal gastrointestinal health. †(Read the blog about the health benefits of probiotics to learn more.)

As a dietary supplement, adults take one (1) capsule daily or as directed by their health care professional. Each box contains 30 vegetarian acid-resistant capsules.

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What Our Customers are Saying

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Reviews of Advanced Daily Probiotic Supplement

  1. I want to let you know that I trust Cooper Complete products very much — I love them all! I feel so great that if I forget some supplement, I realize what is missing. It truly is an overall healthy feeling! Thank you, thank you!

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Customer Q&As

If you have questions, we have answers. See what real people are asking about Cooper Complete products.

15 Questions
Ask a Question
Q:

Is your probiotic dairy-free? Is your company from the US?

A:

The Advanced Daily Probiotic is manufactured in the United States and is formulated to exclude dairy, soy, shellfish, egg, and gluten.

Q:

I can’t swallow capsules. Can I open the capsules and add the powder to something else in order to consume it?

A:

Yes, you may open the capsule and add the powder to something else to consume it.  Keep in mind heat can kill off some of the good bacteria, so we suggest taking it in something at room temperature.

Q:

I am concerned that the heat used to seal the pack might kill the bacteria. Does it still contain the amount of bacteria it states on the label?

A:

We understand your concern. Heat, air, and light can all contribute to the loss of live bacteria over time. That’s why we use nitrogen-purged blister packs to minimize exposure to air and light. In contrast, bottles expose capsules to these elements every time they’re opened, potentially accelerating bacterial die-off.

To ensure the number of live cultures (CFUs) listed on the label is accurate through the expiration date, we include a carefully calculated overage during manufacturing. Any effects from the packaging process, including heat, are accounted for. Additionally, our products are tested by an independent third-party lab to verify that they meet or exceed the labeled CFU count at the time of expiration.

 

Q:

Does the probiotic need to be taken on an empty stomach to be most effective?

A:

The most important factor is taking probiotics consistently. Our probiotics† come in acid-resistant, vegetarian capsules that help deliver them safely to the small intestine, reducing exposure to the stomach’s low pH environment. While some people prefer taking them 20–30 minutes before a meal, daily consistency is generally more important than exact timing.

Q:

I just received a shipment of Advanced Daily Probiotic, and the box was subjected to freezing temperatures for several days as I was out of town. What impact do freezing temperatures have on the probiotic?

A:

Freezing temperatures do not harm probiotics—in fact, they can help preserve their potency. Most probiotics are freeze-dried during manufacturing, which allows them to remain stable at lower temperatures. What typically reduces the viability of probiotics is exposure to heat, moisture, and light—not cold.

Our Advanced Daily Probiotic is packaged in nitrogen-purged blister packs, which offer excellent protection against air and moisture and help ensure product stability through the expiration date. Some people choose to store their probiotics in the freezer to further extend shelf life, although it’s not necessary if the product is kept in a cool, dry place.

So, even after exposure to freezing temperatures, your product should remain safe and effective.

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Q:

Should a healthy 79-year-old woman take this probiotic and your multivitamin?

A:

A multivitamin and probiotic can both support overall wellness. A multivitamin is intended to help fill potential nutrient gaps in the diet†, while a probiotic supports a healthy gut microbiome†.

Probiotics are thought to provide preventive benefits† and support a healthy immune system†. Some people even find that issues such as seasonal allergies may improve with regular probiotic use†.  You can read more about probiotic benefits here.

If you’re considering adding a probiotic to your supplement routine, we recommend discussing it with your healthcare provider to ensure it’s appropriate for your individual health needs.

Q:

Can I use a pill organizer for the Advanced Daily Probiotic?

A:

Because probiotics are living microorganisms, storage is important. They need to be protected from light and moisture. We recommend keeping them in the original blister pack, in a cool, dry location. We recommend not using a weekly pill organizer as they are usually not airtight and could impact the effectiveness of the probiotic.

Q:

Why don’t you store the probiotic in a glass container? I heard those are better than plastic.

A:

Probiotics need to be stored in packaging that protects them from light, moisture, heat, and oxygen—all of which can reduce their potency†. While glass containers are often seen as higher quality, they don’t always provide the best protection against these elements. That’s why we use nitrogen-purged blister packs, which offer superior protection by limiting exposure to air and humidity†. This helps maintain the stability and effectiveness of the probiotic throughout its shelf life†.

Q:

Do probiotics help prevent urinary tract infections?

Also, if taking Cooper calcium and Cooper complete multi, when should probiotics be taken?

 

A:

Antibiotics used to treat urinary tract infections (UTIs) can reduce the number of beneficial lactobacilli bacteria in the urinary system, potentially disrupting its natural defenses. Probiotics may help restore this balance, especially after antibiotic use.

While some research suggests that probiotics may help prevent recurring UTIs, more studies are needed to confirm this benefit. Probiotics are generally safe to take alongside other supplements like Cooper Calcium and Cooper Complete Multi without affecting their effectiveness.

 

Q:

Does this product contain soy?

A:

Cooper Complete Probiotic is formulated to not contain soy but is manufactured in a facility that manufactures products containing soy. Although the equipment is cleaned between product runs, cross-contamination could occur.

Q:

What is your opinion on probiotics for mood and brain health?

A:

As always, we look to scientific research as a basis for our opinion.

Scientific research continues to explore the connection between the gut and the brain—often referred to as the gut-brain axis. Some studies suggest that certain probiotic strains may help support a positive mood and emotional well-being.† For example, Bifidobacterium longum, one of the strains in Cooper Complete Advanced Probiotic, has been studied for its potential role in supporting a healthy stress response.†

While early findings are promising, more research is needed to fully understand the effects of probiotics on mood and brain health. As always, talk with your healthcare provider before starting a supplement for mental wellness.

 

Q:

Should probiotics be taken in the am or pm?

A:

It doesn’t matter whether you take your probiotic in the morning or at night. The most important factor is consistency—take it at the same time each day, whenever it’s most convenient for you.

Q:

Can I take this product if I am also taking anticoagulant medication (i.e., blood thinners)?

A:

If you are taking anticoagulant medication, we recommend consulting your doctor before adding any supplements to your diet.

Q:

Why doesn’t this probiotic supplement require refrigeration?

A:

Advanced Daily Probiotic Supplement vegetarian capsules are acid-resistant (and bile-resistant) and break down in the small intestine rather than the stomach. A cryoprotectant stabilization process makes the vegetarian capsules shelf-stable. Intestinal fluid dissolves the capsule content directly into the small intestine. The capsules are sealed in a nitrogen-purged blister pack to protect from heat, moisture, and oxygen.

This product should be stored in a cool, dry place away from moisture and heat. Do NOT open the nitrogen-purged blister pack until you are ready to take the probiotic supplement.

 

Q:

How many probiotic strains are in the probiotic?

A:

Advanced Daily Probiotic Supplement features four strains that have been clinically researched to support immune and gastrointestinal function including Bifidobacterium lactis NH019, Lactiplantbacillus plantarum, Lactobacillus acidophilus,  and Bifidobacterium longum. As well as Saccharomyces boulardii, (the yeast widely known for its use in kombucha beverages.)

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